logo nano spa 1
  • Cabecera 1
    nanoscience and nanotechnology: small is different
  • Home
  • Advanced Fluorescence Nanoscopy
  • People

Dr. Cristina FLORS

cristina flors

Following my degree in Chemistry, I completed my PhD at the Institut Químic de Sarrià in Barcelona in 2004 under the supervision of Prof. Santi Nonell. During that time, I studied the photophysical properties of phenalenone derivatives, with particular emphasis on singlet oxygen photosensitization, using a range of spectroscopic techniques. In 2005 I moved to the laboratory of Prof. Johan Hofkens at the Katholieke Universiteit Leuven, Belgium, to learn single-molecule and super-resolution fluorescence microscopy. I investigated the photophysical properties of different molecules such as perylene diimide dendrimers and a range of fluorescent proteins. My most representative result from that period was the single-molecule characterization of the photoswitching properties of the fluorescent protein Dronpa and its mutants. Importantly, we showed how the thorough understanding of photophysics can help optimize super-resolution imaging (Flors et al, J. Am Chem. Soc. 2007). Having gained expertise in a new technique with great potential, I moved to the University of Edinburgh in 2008 to begin my independent research career, funded by the Engineering and Physical Sciences Research Council and The Royal Society. I started a new research program to develop methodology for super-resolution imaging of DNA based on single-molecule localization (Flors et al, ChemPhysChem 2009; Curr. Op. Chem. Biol. 2011). In February 2012 I moved to IMDEA Nanoscience with a Ramón y Cajal fellowship, and I am now Senior Group Leader. At IMDEA I continue working on the improvement of super-resolution fluorescence microscopy methods, most recently combining them with atomic force microscopy. In parallel to the super-resolution work, I am also interested in the photosensitizing properties of fluorescent proteins and their applications in advanced microscopy and phototherapy.

Phone: +34 912998767

Position: Senior Research Prof.

This email address is being protected from spambots. You need JavaScript enabled to view it.

 

researchID ORCID.png googlescholar

 

Dr. Alberto RODRIGUEZ-PULIDO

alberto rpulido

I received my PhD in Chemistry from the Complutense University of Madrid, Spain, in 2009. In the group of Prof. Emilio Aicart & Prof. Elena Junquera, I investigated biocompatible DNA-carriers (-liposomes and -micelles) which could be explotaible for gene therapy. In 2010 I moved to the Zernike Institute for Advanced Materials at the University of Groningen, the Netherlands. In the group of Prof. Andreas Herrmann, I improved my expertise in imaging and biophysical techniques, oligonucleotide- and peptide-functionalization and payload delivery. My most successful achievement consisted in developing DNA-block copolymer-functionalized nanobiocontainers which are sequence-specifically programmed to release cargo by hybridization with complementary DNA-photosensitizer conjugates.
Looking for industrial applicability to my research, during 2013 I had also the chance to manage, design and implement a R&D project based on functionalized nanovehicles passing through the stratum corneum, at a cosmetic startup company. After that, I was awarded with an Experienced Research AMAROUT-II fellow to join IMDEA-Nanoscience Institute. Since 2014, I am working with Cristina Flors, investigating more efficient genetically-encoded singlet oxygen photosensitizers in order to improve photodynamic therapy and electron microscopy.

Phone: +34 912998898

Position: Postdoctoral Researcher

This email address is being protected from spambots. You need JavaScript enabled to view it.

 

ORCID.png googlescholar

 

Patricia BONDIA

patricia bondia

The development of new technologies to study the assembly of nanoscale events that rule every biological process has become my motivation for doing research since I studied Biotechnology (Polytechnic University of Valencia and Ghent University, 2013). During that time, I had the opportunity to work at the molecular biology lab at the IBMCP (Valencia), where my interest in the control of protein expression and genetic engineering began. I was fascinated by the applications of molecular biology in Biomedicine, and I decided to join the pharma industry becoming part of the Protein Science group of Crucell B.V. (Leiden, The Netherlands). There I discovered the power of biophysics to understand the protein nanoworld. Afterwards, I decided to enrol in the Biophysics master (Autonomous University of Madrid, 2014) and focus my master thesis on studying the role of proteins as a mechanical signal transductor through force spectroscopy at the Cajal Institute (Madrid). During this master, I was given the chance to discover state-of-art technology used in molecular biology research, and the new high resolution imaging techniques like super-resolution fluorescence microscopy captured my attention.

As a result, I am now doing my PhD in the group of Cristina Flors. My studies are focused on the application of super-resolution fluorescence microscopy in correlation with AFM for the nanoscale study of biological structures with potential application in biomedicine and materials science.

Phone: +34 912998765

Position: PhD Student 

This email address is being protected from spambots. You need JavaScript enabled to view it.

Adrián DEL VALLE

adrian valle

I started my academic training at the Polytechnic University of Madrid (UPM, 2014), where I studied Technical Industrial Engineering, with a specialization in Industrial Chemistry. During this stage, I was able to build a solid engineering base and begin to deepen my knowledge in advanced chemistry. I developed a heat pump installation to improve energy efficiency in a continuous distillation system, which allowed me to win the Gas Natural Fenosa award to the best final degree project in the chemical engineering area. I then enrolled at the Chemical Engineering Master at the Autonomous University of Madrid (UAM, 2016). For my master thesis I developed ceramic scaffolds for bone regeneration at the Institute of Ceramics and Glass in Madrid, and spent some time at the Belgian Ceramic Research Center in Mons, where I used the freeze-casting technology. I found this experience very fascinating, so I decided to immerse myself into research. Currently, I work in IMDEA Nanoscience, doing my PhD in the group of Cristina Flors. My objectives are to extend the potential of correlative super-resolution fluorescence microscopy and atomic force microscopy, and use this tool in microbiology.

Phone: +34 912998748

Position: PhD Student 

This email address is being protected from spambots. You need JavaScript enabled to view it.